Lianhe Aigen offers specialized ADC Linker Pharma Services designed to advance the development of Antibody-Drug Conjugates (ADCs), a groundbreaking therapeutic approach in precision oncology and beyond. With a robust ADC/PROTAC Linker Platform, we provide comprehensive solutions for the design, synthesis, and production of high-quality linkers, empowering the next generation of targeted drug delivery systems.

Why ADC Linkers Are Critical

ADC linkers play a pivotal role in the stability and efficacy of ADCs, ensuring precise delivery of potent cytotoxic agents to target cells while minimizing off-target effects. At Lianhe Aigen, we leverage cutting-edge technologies and years of expertise to develop innovative linker chemistries that optimize therapeutic outcomes.

Our ADC Linker Services and Capabilities

1. Custom Linker Design and Synthesis:

Tailored linker solutions, including cleavable, non-cleavable, hydrophilic, and multifunctional linkers.

Expertise in creating stable linkers with controlled release mechanisms for improved therapeutic performance.

2. Advanced R&D and Manufacturing Platforms:

ADC/PROTAC Linker Platform: Dedicated to high-precision linker development and seamless integration with antibody and payload components.

State-of-the-art facilities for small- to large-scale linker synthesis, adhering to strict quality and regulatory standards.

3. GMP-Grade Production:

Manufacturing facilities certified by global regulatory bodies, including FDA, EMA, and PMDA, ensuring compliance for clinical and commercial use.

Rigorous quality control processes to ensure consistency, purity, and safety of linker products.

4. Analytical Expertise:

Comprehensive analytical support for structural characterization, stability testing, and impurity profiling of ADC linkers.

Advanced techniques such as HPLC, LC-MS, and NMR to meet stringent pharmaceutical standards.

5. Regulatory and Technical Support:

Support for IND, DMF, and other regulatory submissions to streamline clinical approval processes.

Full documentation and technical consultation tailored to your project needs.

6. Seamless Integration for ADC Development:

Collaborative development services to integrate linker synthesis with payload conjugation and antibody coupling.

Solutions optimized for stability, efficacy, and scalability in preclinical and clinical applications.

Applications of ADC Linkers

Lianhe Aigen provides linkers suitable for a broad range of therapeutic applications, including:

Oncology: Targeted delivery of cytotoxic agents for cancer treatment.

Autoimmune Diseases: Precision-targeted biologics for immune modulation.

Infectious Diseases: ADCs for pathogen-specific targeting.

Empowering ADC Innovations with Lianhe Aigen

As a trusted partner in the pharmaceutical industry, Lianhe Aigen is committed to accelerating the development of ADC therapies through innovative linker chemistries and world-class manufacturing capabilities. By delivering high-quality, reliable solutions, we enable pharmaceutical innovators to bring life-changing therapies to patients worldwide.